Evaluation of performances of VERSANT HCV RNA 1 . 0 assay ( kPCR ) and Roche COBAS
نویسندگان
چکیده
9 We assess the concordance between low level HCV values obtained using the VERSANT HCV RNA 10 1.0 Assay (kPCR) and COBAS AmpliPrep/COBAS TaqMan HCV Quantitative Test v2.0. 11 The correlation between the values obtained by the two RT-PCR assays for samples with quantifiable 12 HCV RNA levels revealed that viral load measured by kPCR significantly correlated with that of the 13 CAP/CTM (R=0.644, P <0.0001). The results show a good concordance (n=126/144, 87%); 14 discordant results were mainly observed in the assessment of values below the lower limit of detection 15 of the assays. 16 These variations may have an impact on clinical decisions for patients on HCV triple therapy or 17 interferon-free regimens. It is therefore recommended to monitor individual patients with the same 18 test throughout treatment. 19
منابع مشابه
Evaluation of performances of VERSANT HCV RNA 1.0 assay (kPCR) and Roche COBAS AmpliPrep/COBAS TaqMan HCV test v2.0 at low level viremia.
We assess the concordance between low level HCV values obtained using the VERSANT HCV RNA 1.0 Assay (kPCR) and COBAS AmpliPrep/COBAS TaqMan HCV Quantitative Test v2.0. The correlation between the values obtained by the two RT-PCR assays for samples with quantifiable HCV RNA levels revealed that viral load measured by kPCR significantly correlated with that of the CAP/CTM (R=0.644, P<0.0001). Th...
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